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BioEngine Raises Another RMB 200 Million, Continues to Promote the "Made in China" Serum-Free Culture Media

Time:Mar 29,2022

Recently, China's leading company in animal cell culture technology and domestic serum-free culture media, Shanghai BioEngine Sci-Tech Co., LTD, announced the completion of a 200 million RMB Series B++ financing round. The financing was led by Legend Capital, followed by Addor Capital and Tsing Song Capital, and the old shareholder Hankang Capital continued to increase the capital.

"Insisting on technological innovation and R&D for decades, insisting on making real high quality 'Intelligent Manufacturing in China' serum-free culture medium is the hard but right thing to do." Dr. Wensong Tan, Chairman of BioEngine, said, "In terms of serum-free medium localization, only by relying on rich domestic raw material resources, having sustainable local R&D and innovation capabilities and cutting-edge production and quality management capabilities can we achieve true 'Intelligent Manufacturing in China' serum-free medium. We would like to express our sincere gratitude to the investment institutions that participated in this round of financing and the original investors for their recognition and support. This round of financing reinforces our determination to continue to build a new impetus for Chinese cell culture and to take the path of 'Intelligent Manufacturing in China' serum-free culture medium. The funds raised in this round will continue to be invested in the innovation and development of technology and products as well as the re-upgrading of production and quality management capabilities, to promote the establishment of production and quality management standards and norms in the domestic serum-free medium industry, to completely solve the 'containment' problem of key raw materials for cell culture, and to continuously empower the vigorous development of the biopharmaceutical industry. "

 

Legend Capital said,

We are pleased to have Legend Capital as the lead investor in this round of financing. As one of the important core raw materials in the upstream of innovative biotechnology, such as biopharmaceuticals, vaccines, gene, and cell therapy, cell culture media plays an irreplaceable role in supporting and guaranteeing, and the need to solve the "containment" risk is becoming more and more urgent, with huge development space. Relying on the academic, technical, and application accumulation of the "only Chinese national team" of cell culture for more than 30 years, Bechtel has continuously innovated and made breakthroughs and realized the real meaning of independent control and large-scale localization in the fields of formula design, production process, and supply chain system, and its products and services are widely recognized. Legend Capital, as a leading domestic venture capital institution, aims to help companies grow and innovate through capital and management. Legend has always focused on innovation and growth investments in upstream life science-related industries and has built an industry ecosystem covering innovative medicine, biotechnology, upstream core raw materials, and equipment. We expect Betsy to leverage this round of financing to continuously optimize the technology platform and service system, accelerate product upgrade and commercialization promotion, and lead the development of the core raw material and equipment industry. We will also closely link with customers and partners to enhance the value of the industry, gradually form a global brand influence, and help China's biopharmaceutical industry take off.

Addor Capital said,

Culture media is the blood of biopharmaceuticals, and BioEngine is one of the companies with the deepest technology accumulation, the most abundant product pipeline, and the largest industrialization scale in China. Currently, the products of BioEngine have covered hundreds of customers, ranging from animal vaccines, human vaccines, antibody drugs, gene/cell therapies, etc. Bechtel has assisted several downstream customers to complete the registration and commercialization of their products. Addor Capital is honored to participate in this investment and we will continue to support the development of the company together we will assist the company to better serve domestic-related companies.

Tsing Song Capital said,

We are very pleased to participate in this round of financing. As one of the most important upstream raw materials in the biopharmaceutical field, culture media is also a key consumable that faces the risk of "containment" and has great potential for development. In addition to having the leading technology level of cell culture media and upstream process development of biopharmaceuticals in China, BioEngine has also been widely recognized by industry users for its culture media manufacturing and quality management level. In recent years, BioEngine has introduced world-class production technology and an international advanced quality management system to realize the scale, informatization, and internationalization of domestic culture media production, and has grown into a benchmark enterprise of high-quality culture media manufacturers in China. Together with our strategic partners, we continue to focus on and support the development and innovation of the upstream supply chain to provide a safe and high-quality development foundation for the biopharmaceutical industry. We expect that with the support of this round of financing, BioEngine will accelerate the technology upgrade and commercialization of its products and services, build an industry-leading technology platform and service system, and provide customers with more high-quality, safe, and stable products and services.

Hankang Capital said,

Innovative antibodies, vaccines, and cell therapy products continue to create benefits for patients and are one of the main driving forces behind the rapid development of China's biopharmaceutical industry. Serum-free medium is a key raw material for biopharmaceutical production, and the R&D innovation and industrialization of cell culture technology and medium brands and the gradual localization in the industry are also in line with the direction of national support for specialized and new industries. Since the investment of Han Kang Capital, Bechtel has continued to innovate and develop, and its ability and strength of manufacturing high-performance serum-free culture medium with international quality has been fully tested by the market and highly recognized by customers. We are grateful to the new investors for joining us and working together with our team to promote the "Intelligent Manufacturing in China" of key raw materials of international quality.

About BioEngine

Shanghai BioEngine Sci-Tech Co., Ltd was established in December 2014, focusing on large-scale high-density serum-free suspension culture technology services and raw material development and manufacturing for animal cells, providing biopharmaceutical companies with high-quality one-stop services from cell culture process development and optimization, medium formulation design to medium processing and manufacturing.

Since its establishment in 2014, BioEngine has grown very rapidly. We have developed nearly 100 types of serum-free media, supported more than 60 clinical projects in the biopharmaceutical industry, such as an antibody, vaccine, and stem cell/cell therapy, and provided nearly 100 cell culture technology services. The company has many  innovative project achievements domestical and international. The quality of our products and technical services have surpassed those of similar imported products, and are highly appreciated by domestic biopharmaceutical companies.

At the end of 2021, the Phase II culture media localization base (Shanghai Beijin Biotech Co., Ltd) was put into full operation. The base is a world-class factory built following ISO13485:2016 quality management system and GMP requirements, adopting LSS Lean 6 Sigma system for production management, achieving a thousand upgrades, ten thousand upgrades, one hundred thousand upgrades of low-temperature needle mill powder process consistency amplification, the maximum batch can reach 100,000 liters, with an annual capacity of 55 million liters of powder culture medium and 250,000 liters of liquid culture medium. The production base is expected to pass ISO13485 and FDA system certification in 2022, helping customers to realize dual reporting in China-USA and China-Europe.

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