Products
BioEngine has developed nearly 100 types of serum-free media for different cell lines, which are suitable for antibodies, vaccines and cell and gene therapy (CGT) fields.
The founding team of BioEngine started the study of in vitro culture of lymphocytes in the 1990s and had made great scientific achievements in this area. For prospective clinical application, the R&D team of BioEngine initiated the design and development of serum-free media for culturing of lymphocytes in vitro in 2015, and successfully obtained a completely serum-free medium formulation in 2018 which was launched with the name of HIPP-T009 in the same year. In 2020, HIPP-T009 became the first homegrown culture medium product used in cell therapy clinical trials in China.
HIPP-T009 is an ideal choice for large-scale culture of lymphocytes. It demonstrates not only excellent performance on cell expansion and functional expression but also ensures high safety and stability of the culture process since no serum or other serum substitutes are needed in the culturing system. As HIPP-T009 contains no exogenous cytokines or activators, corresponding cytokines or activators should be added if necessary.
HIPP-T009 serum-free medium for lymphocytes
Xeno-free, contains no growth factors, synthetic activators, or undefined components
Universality and flexibility: Applicable for the culture of T-cell, NK cell, CAR-T, CIK, CAR-NK, hematopoietic stem cells and other types of cell lines (NK-92, NK-92MI, K562, Jurkat, etc.)
High performance in cell expansion and high-density culture under completely serum-free condition
The 1st approved Chinese culture medium used in cell therapy clinical trials;
No need to add serum, plasma, or serum substitutes, hence it minimizes batch-to-batch variation in the culture process and simplifies the declaration process for IND/NDA applications;
Manufactured under the cGMP guidelines and ISO13485 quality system, meet regulatory requirements in different countries;
Innovative “2 domestic+1 imported” raw material supplier modal ensures a stable supply chain to face the fluctuations and uncertainty in the raw material market;
The comprehensive set of DMR documents for audit.
Xeno series and SF003 medium are suitable for high-density culture and efficient proliferation of MDCK cells, supporting rapid serum-free suspension adaptation of adherent MDCK and efficient amplification and production of influenza viruses.
We have a professional technical team to provide high quality one-stop cell culture service from process development
and optimization, medium formulation design to medium processing and manufacturing for all biopharmaceutical companies.
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3F&4F, Building 3, Lane 396, Lvzhou Ring Road, Minhang District, Shanghai, PRC